1、What problem do you have?
例句：不管你有什么问题，来找我帮忙好了。
No matter what problems you have, come to me for help.
2、What's wrong with you?
例句：You look terrible. What’s wrong with you?
你看起来不太好，你有什么问题吗？
3、Have you got anything to ask ?
例句：That's all about our school.Have you got anything to ask ?
以上就是我们学校的情况，你还有什么问题吗？
4、Have you got any problem?
例句：安娜，怎么了？你有什么问题吗？
What's the matter Anna? Have you got a problem?
5、Do you have any question to ask?
例句：对这份工作，你有什么问题要问吗？
Do you have any questions to ask about this job?
yuanning2008
